PUFA dangers part 5: Androgens, estrogen, prolactin & cortisol

PUFAs, when incorporated into cell membranes, cause the cells to become more fluid, are chaotropic, disorderly and reduce their function (1). Steroids are made in the mitochondria and require lots of ATP (energy molecule of the cells) to synthesize steroid optimally. Low ATP = low steroidogenesis. Steroidogenesis requires cholesterol, vitamin A, thyroid hormones, NAD+, magnesium … Continue reading PUFA dangers part 5: Androgens, estrogen, prolactin & cortisol

The High Serotonin Personality

Serotonin is a complicated neurotransmitter that, contrary to other neurotransmitters, has an influence on everything in the body. It's currently believed to aid in anxiety, depression, impatience, impulsiveness, anger, etc. One of the main reasons for this is that the metabolite of serotonin, 5-HIAA, is low in people with these symptoms. The research is thus … Continue reading The High Serotonin Personality

PUFA dangers Part 4: Influence on Cellular & Thyroid function and Diabetes

Polyunsaturated fat (PUFAs), when incorporated into cell membranes, make cells more fluid, are chaotropic and disorderly and reduce their function (1). The increase in fluidity will allow more water, sodium, chloride, and calcium into the cell (edema), and lower intracellular potassium and magnesium and this will also destabilize the cell, and reduce cellular function (2). Metabolic … Continue reading PUFA dangers Part 4: Influence on Cellular & Thyroid function and Diabetes

MCT oil, liquid rocket fuel

Medium-chain triglyceride (MCT) oil is commonly known for its potent ability to aid in fat loss. However, this oil contains much more benefits, which I will discuss in this article. First and foremost, fatty acids can be divided into four groups. These are short-chain- (SCFAs), medium chain- (MCFAs), long chain- (LCFAs) and very long chain … Continue reading MCT oil, liquid rocket fuel

Does Niacinamide contribute to diabetes and insulin resistance?

Vitamin B3 comes in a few forms, with niacin (nicotinic acid (NA)), niacinamide (NAM), nicotinamide riboside (NR) and inositol hexanicotinate being the most famous. As you can see from the picture, vitamin B3 can come in three forms from the diet, namely NA, NAM and NR, whereas an endogenous pathway can also synthesize NAM from … Continue reading Does Niacinamide contribute to diabetes and insulin resistance?

Different fats and inflammation

Let me just start off by saying that fat gain happens mostly in the presence of caloric excess (when more calories are consumed than is being burned). For healthy adipose tissue expansion, there needs to be acute inflammation, collagen remodeling and growth of new blood vessels (angiogenesis). Without these factors, healthy fat gain cannot take … Continue reading Different fats and inflammation

Reactive oxygen species created by fats and their affect on insulin signalling

Does fat make you fat? And if the answer is yes then which type of fat is the guilty one? Fat mass expansion in obesity occurs via adipocyte hyperplasia (increased adipocyte number) and/or adipocyte hypertrophy (increased size of adipocytes). The latter is often associated with adipose dysfunction and inflammation. Increased adipocyte size correlates with serum … Continue reading Reactive oxygen species created by fats and their affect on insulin signalling

Omega 6 busts your electron transport chain

The mitochondria, also called the "powerhouse" of the cells, is where ATP is made. Cells use fats, carbohydrates and sometimes a little protein to create energy. These macronutrients are broken down in the cell to provide electrons for the electron transport chain, creating a mitochondrial membrane potential (Δψm). Complex I, III, & IV, powered by … Continue reading Omega 6 busts your electron transport chain