46 ways to increase DHT (2018 update)

  DHT was always thought to be converted from testosterone, however, recent data suggest that instead, it's converted from Δ-androstenedione by 5α-reductase isoenzyme-1 to 5α-androstanedione, followed by subsequent conversion to DHT via the enzyme 17β-hydroxysteroid B3. The 5α-androstanedione pathway to DHT, therefore, bypasses testosterone entirely (1). Androstenedione → 5α-androstanedione → DHT. Also, "DHT formation from 4-dione (androstenedione) increased gradually and … Continue reading 46 ways to increase DHT (2018 update)

Signs of low dopamine and the top 5 supplements to increase it

Dopamine is a very important neurotransmitter synthesized in the brain. It is synthesized from phenylalanine, tyrosine or L-DOPA. Tyrosine is converted into L-DOPA via the enzyme tyrosine hydroxylase (TH), which requires vitamin B6 as a cofactor, and then L-DOPA is converted to dopamine. Once dopamine is released from neurons, free dopamine is pumped out of the … Continue reading Signs of low dopamine and the top 5 supplements to increase it