46 ways to increase DHT (2018 update)

DHT was always thought to be converted from testosterone, however, recent data suggest that instead, it's converted from Δ-androstenedione by 5α-reductase isoenzyme-1 to 5α-androstanedione, followed by subsequent conversion to DHT via the enzyme 17β-hydroxysteroid B3. The 5α-androstanedione pathway to DHT, therefore, bypasses testosterone entirely (1). Androstenedione → 5α-androstanedione → DHT. Also, "DHT formation from 4-dione (androstenedione) increased gradually and was … Continue reading 46 ways to increase DHT (2018 update)

60 Best ways to lower Serotonin

Serotonin is always thought of being the happy hormone and that by increasing it has an anti-depressant effect. As a matter of fact, the majority of anti-depressants is selective serotonin reuptake inhibitors, and more than 90% of the people on anti-depressant medication is on SSRI. Before SSRI became so popular, there were studies done showing … Continue reading 60 Best ways to lower Serotonin

27 ways to increase free testosterone & lower SHBG

You want as much free testosterone as you can get so there can be optimal interaction with androgen receptors for optimal anabolic activity. So after testosterone leaves the testes and enters the bloodstream (that's total testosterone), about 44–65% of the circulating plasma T is bound strongly to sex hormone binding globulin (SHBG) and 33–54% binds … Continue reading 27 ways to increase free testosterone & lower SHBG